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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Tofacitinib (CP-690.550) Influence on protein activity in presence of IFNγ Western Blot 0.30 nM Naïve CD4+ T Mus musculus c57BL/6 p-STAT1
Tofacitinib (CP-690.550) Influence on protein activity in presence of IFNγ Western Blot 0.30 nM Naïve CD4+ T Mus musculus c57BL/6 STAT1
Tofacitinib (CP-690.550) Influence on protein activity in presence of IL-4 Western Blot 0.30 nM Naïve CD4+ T Mus musculus c57BL/6 p-STAT6
Tofacitinib (CP-690.550) Influence on protein activity in presence of IL-4 Western Blot 0.30 nM Naïve CD4+ T Mus musculus c57BL/6 STAT6
Tofacitinib (CP-690.550) Influence on protein activity in presence of IL-2 Western Blot 0.30 nM Naïve CD4+ T Mus musculus c57BL/6 p-STAT5
Tofacitinib (CP-690.550) Influence on protein activity in presence of IL-6 Western Blot 0.30 nM Naïve CD4+ T Mus musculus c57BL/6 STAT5